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Bram Estes

Bram Estes is a Senior Principal Scientist at Amgen, Thousand Oaks. Bram received his B.S in Biochemistry and Cell Biology from the University of California in San Diego in 2001. Between high school and college, he spent seven years racing bicycles across the United States and Europe. He began his career studying agricultural plant and pathogen relations by reverse genetics at Novartis and Syngenta. He then shifted his focus to biopharmaceutical protein production at Xencor. In his 19 years at Amgen, Bram has had an assortment of roles, including developing high volume and automated high-throughput expression platforms, developing immunoglobulin scaffolds for monoclonal antibody and multi-specific therapeutics, and engineering therapeutic proteins for improved biophysical characteristics. He has also led numerous therapeutic projects through research and early development and leads the expression group in the Large Molecule Discovery department.

 

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